Global Health Asia-Pacific March 2020 | Page 62

Endometriosis Scant research on endometriosis means women’s voices are left unheard Cultural taboos and GP reticence mean diagnosis of the abnormal lining of the uterus is often delayed by years W This misplaced tissue acts like it would in the uterus, thickening, breaking down, and bleeding with each menstrual cycle but has no way to leave the system and becomes trapped 60 MARCH 2020 ith a perplexing progression and a seemingly high incidence rate, endometriosis appears to be more widespread in Asia than in any other region of the world. The condition occurs when tissue similar to what normally lines the uterus, known as the endometrium, grows outside it, at times causing tremendous pain. Despite its apparent prevalence in the region, a cultural reluctance by doctors and patients to discuss gynaecological matters often delays diagnosis, leaving many women finding out too late that they have the condition. Endometriosis most commonly involves the ovaries, fallopian tubes, and the tissue lining the pelvis. In some cases, endometrial tissue may spread beyond the pelvic area to other organs, including the lung and bowel. This misplaced tissue acts like it would in the uterus, thickening, breaking down, and bleeding with each menstrual cycle but has no way to leave the system and becomes trapped. When this happens in the ovaries, cysts called endometriomas may form. Surrounding tissue can become irritated, eventually developing scar tissue and abnormal bands of fibrous tissue known as adhesions that can cause pelvic tissues and organs to stick to each other. Despite research, endometriosis remains an enigmatic disease with an as yet unknown cause. According to a recent review, there is growing evidence that hormonal and immune factors create a pro-inflammatory microenvironment that encourages the persistence of endometriosis. This also relates to the disease’s two main symptoms of pain and infertility. Endometriosis can cause pain that is sometimes severe, especially during periods. It’s also common for patients to experience pain during or after sex, excessive bleeding, and difficulty with urination and bowel movements. Infertility can be another symptom. Though there is no cure, medical and surgical options are available to help reduce the symptoms and manage potential complications. Over-the-counter medication, such as ibuprofen, is not always effective. Taking supplemental hormones can sometimes relieve pain and stop the progression of endometriosis by regulating the monthly hormonal changes that promote tissue growth. By preventing the monthly buildup of endometrial tissue, birth control pills, patches, and vaginal rings can reduce or even eliminate the pain in less severe endometriosis. For women with severe pain for whom hormonal treatments do not work, conservative surgery to remove or destroy endometrial growths is a possibility. Laparoscopy, a minimally invasive surgery, is used to both visualise and diagnose endometriosis and to remove the endometrial tissue. A surgeon makes small incisions in the abdomen to surgically remove the growths or burns or vaporises them. But lasers are now more commonly used to destroy the misplaced tissue. GlobalHealthAndTravel.com