ALPHA IVF GROUP

Collectively with Genesis IVF & Women ’ s Specialist Centre ( Penang ), Alpha IVF ( Kuala Lumpur ), and Alpha IVF ( Singapore ), the Alpha IVF Group was once again awarded with the Fertility Service Provider of the Year in the Asia-Pacific by Global Health Asia-Pacific . It was its fourth consecutive year bagging this award . Let ’ s take a closer look on how it manages to boost the success rate for its patients through artificial intelligence ( AI ).

Boosting IVF Success Rate with AI In line with today ’ s fast-paced digital transformation where AI-powered automation software has become the mainstream , Alpha IVF Group has taken an avant-garde approach by utilising AI for In-Vitro Fertilisation ( IVF ) to optimise and increase its patients ’ success rates . Its active involvement in the research and development of AI in IVF practice since 2018 , along with other AI innovators from Australia , the USA , Denmark , Israel , and Poland , has produced fruitful results where its AI-enhanced embryo selection is demonstrating a 25 percent improvement in accuracy in choosing the embryo for transfer as compared to the conventional embryologist morphology assessment .

Alpha IVF achieved the first healthy live birth following the transfer of embryos selected using AI in Southeast Asia in 2021 ( Lim AYX et al , OGSM 2021 ). Subsequently , in June 2022 , Alpha IVF and Presagen ( USA & Australia ) published a groundbreaking result where a novel AI algorithm called ‘ Life

Margaret Wong

Whisperer Genetics ’ was developed to assess the genetic integrity of embryos non-invasively using only images . This study was published in the Human Reproduction Journal ( Diakiw et al , 2022 ), and its results brought new hope to IVF patients .

The development of an AI model for predicting the likelihood of human embryo euploidy based on blastocyst images from multiple imaging systems during IVF will greatly assist physicians and embryologists in selecting the most viable embryo for transfer . Built using deep machine learning , the AI algorithm identifies traits from huge embryo databases worldwide with previous successful pregnancies . Through an assessment of the known components of the embryo that indicate its quality and the more complex patterns of the embryo that are too difficult to assess through human eyes , the AI software combines these different contributions in the right proportion and generates an AI Score .

In a nutshell , it means that embryo images taken from the time-lapse imaging system will be collected and analysed by the AI-enhanced embryo selection software . The software algorithm scans the images and generates a score of up to 10 based on the implantation potential and likelihood of creating a pregnancy , whereby a higher score indicates a higher chance of implantation . Besides its in-house embryo selection system , Alpha IVF Group uses three types of AI tools that correlate with embryo viability , euploidy prediction , and likelihood of implantation to assist in selecting the best embryo for transfer with the aim of achieving a successful pregnancy in the shortest time .

With centres located in Kuala Lumpur , Penang , and Singapore , Alpha IVF Group is one of the premier conception clinics in the country , with one of its centres having recorded an IVF success rate of 82.9 percent . Topped with cutting-edge technology and a revolutionary AI approach , Alpha IVF Group aims to bring new hope to women undergoing IVF through selection of the best embryo at a faster speed for a quicker conception , which ultimately lessens the strain of IVF on them , their spouse , and families .

86 SEPTEMBER 2022 GlobalHealthAsiaPacific . com